![]() I had surgery many times, and did not want to relive this experience again in old age. I was sure that I would not have arthritis over time. Mayo Clinic.I’ve been involved in sports all my life, and I know what a sports injury is. Mayo Clinic.Ĭonventional Platelet-Rich Plasma Versus Concentrated Bone Marrow Stem Cell Injections for Osteoarthritis of the Knee. For more informationĪ Study of the Safety and Usability of Culture Expanded STEM Cells Derived from the Patient's Own Fat Tissue for Treatment of Knee Osteoarthritis. And researchers at Mayo Clinic's campus in Jacksonville, Florida, are conducting clinical trials comparing conventional PRP treatment with concentrated bone marrow stem cell injections for osteoarthritis of the knee. Smith and colleagues are conducting FDA-approved clinical trials on the use of purified stem cells to treat knee arthritis. In addition to treating patients with PRP and BMAC, Dr. ![]() PRP and BMAC are not yet approved by the Food and Drug Administration (FDA) for use in treating osteoarthritis pain and therefore are typically not covered by insurance. I strongly believe that the healthier you are, the more likely these treatments are to succeed." They are only as healthy as the people they come from. "One of the things I feel is relevant to her success is that she's very healthy," Dr. Smith notes that the patient's overall health contributed to the treatment's chance of success. The patient indicated that the injections eased the pain enough for her to return to her previous level of activity.ĭr. Smith says.Ī few hours after receiving treatment, the patient walked out of the procedure room with the aid of crutches and a knee brace, which she used for one week. "The bone marrow concentrate and platelet rich plasma very naturally modify the inflammatory and immune response," Dr. The bone marrow is drawn from a patient's pelvic bone, concentrated in a centrifuge and then injected into the problematic area. They also have the ability to become other types of cells. Stem cells also have significant anti-inflammatory properties and can powerfully influence other cells involved in inflammation and healing. The concentrate is then injected back into the patient's joint, where the growth factors mitigate inflammation.īMAC contains not only platelets but also a variety of other powerful cells, including stem cells. "They are the first responder cells when we get injured, and they control the damage and start the healing process."įor PRP therapy, platelets are extracted from a vein in the patient's arm and concentrated using a centrifuge. "Treatment with PRP is built upon the knowledge that platelets carry a multitude of growth factors," Dr. What is known about the treatments is that they most likely lessen the inflammatory process caused by degrading joint cartilage. "We tell our patients that it's an acceptably safe orthopedic procedure, and it may or may not modify their level of pain," Dr. Smith says that a portion of the conversation he has with patients is that regenerative medicine strives to restore health by harnessing the body's natural ability to heal itself. ![]() "But we have a pretty good success rate when the primary goal is to improve symptoms and allow patients to do the things they want to do."ĭr. ![]() "It doesn't work 100 percent of the time," he says. ![]() Current scientific literature indicates that between 40 and 70 percent of individuals who receive this treatment find some level of pain relief, according to Dr. Smith and colleagues at Mayo have administered PRP or BMAC injections in more than 400 patients. Jay Smith, M.D., a physiatrist and the director of Regenerative Medicine within the Rehabilitation Medicine Research Center at Mayo Clinic's campus in Rochester, Minnesota, evaluated the patient and administered the BMAC and PRP injections. In July, she received an injection of bone marrow aspirate concentrate (BMAC) and PRP. The PRP injections alone did not provide adequate symptom relief. In January 2015, the patient had received two separate injections of platelet-rich plasma (PRP). ![]()
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